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apalutamide will reduce the extent or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with drugs which can be CYP3A4 substrates may end up in lower exposure to those prescription drugs.This isn't a complete list of probab

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